Family name Ruzhena (Ружена 
, Ружана , Ruzhena 
) , globally, is a very rare surname. The cognomen Ruzhena is characteristic of Armenia, where it is a rare surname, Bulgaria, and Kyrgyzstan, where it is a very rare surname. Not in comparison with a country's population, it most frequently occurs in Bulgaria, Armenia, and Russia. Much more frequently, Ruzhena is the forename as well as the last name.
Pysak, Rusak, Rzhyska, Shulman, Blumkin, Fayerman, Saltisky, Sikarova, Romanyuk, Dervishi, Vasylenko, Vorobyeva, Afanasyeva, Chekhanovskaya, and Trakhtenberg