Family name Rodriguez Santacruz (Rodriguez Santacruz 
) , across the world, is a very rare surname. The family name Rodriguez Santacruz is habitual in Ecuador, where it is a rare surname, Spain, where it is a very rare surname, and Mexico, where it is an extremely rare surname.
| VARIANT | COUNTRY |
|---|---|
| Rodriguez Santacruz | Mexico, Spain, United States, Ecuador |
Carolina, Sol Maria, Alejandro, Maria Luisa, Juan Andres, Andres Felipe, and Maria Alejandra