Family name Pierna (Pierna 
) , throughout the world, is a rare last name. The cognomen Pierna is characteristic of Argentina, where it is a rare surname, the Dominican Republic, and Spain. Measured by absolute frequency, it is the most numerous in Argentina, Spain, and the United States. More frequently, Pierna is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Pierna | Spain, United States, Argentina, Democratic Republic of the Congo, France |
| louis pierna French politician, FR (b. 1933) |
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| milagros pierna ES (b. 1957) |
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| carmen piernas researcher ORCID ID = 0000-0002-7536-922X |
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