Family name Opilio (Opilio 
) , around the world, is a very rare surname. The family name Opilio is characteristic of Italy, where it is a very rare surname, and Nicaragua. More prevalently, Opilio is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Opilio | Italy, United States, Ecuador, India, Brazil |
| venantius opilio Imperial Roman consul (b. 524) |
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antonius opilio Attorney at law and Certified court expert, AT (b. 1965) |
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