Surname Mesplé (Mesplé 
) , throughout the world, is a very rare cognomen. The cognomen Mesplé is characteristic of Western Europe, particularly France, where it is a very rare surname.
| henri andré mesplé French military personnel (1863-1935), FR (b. 1863) |
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| marie mesplé French Righteous Among the Nations, FR (b. 1868) |
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mady mesplé French soprano (1931-2020), FR (b. 1931) |
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louis mesplé French journalist, FR (b. 1949) |
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| gaston mesplé FR (b. 1892) |
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| paul mesplé (b. 1896) |
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| victor mesplé FR (b. 1898) |
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| henriette mesplé French Righteous Among the Nations, FR |
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| marie-jeanne mesplé French Righteous Among the Nations, FR |
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