Cognomen Luisa Penelope (Luisa Penelope 
) , throughout the world, is an extremely rare surname. The last name Luisa Penelope is characteristic of Latin America and the Caribbean, particularly Chile, where it is an extremely rare surname. Much more prevalently, Luisa Penelope is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Luisa Penelope | Peru, Chile, Dominican Republic |