Surname Lopez De Los Santos (Lopez De Los Santos 
) , around the world, is a rare cognomen. The surname Lopez De Los Santos is characteristic of the Dominican Republic, where it is a rare surname, Spain, and Chile, where it is a very rare surname. Not in comparison with a country's population, it most frequently occurs in Spain, the Dominican Republic, and Mexico. Much less frequently, Lopez De Los Santos is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Lopez De Los Santos | Mexico, Spain, Dominican Republic, Ecuador, Chile |
Oscar, Manuel, Sergio, Gloria, Javier, Vanesa, Damaris, Alejandro, Mary Celia, Maria Elena, and Maria Del Carmen