Family name Isaza Ospina (Isaza Ospina 
) , globally, is a very rare last name. The cognomen Isaza Ospina is characteristic of Latin America and the Caribbean, particularly Colombia, where it is a very rare surname, and Ecuador.
| VARIANT | COUNTRY |
|---|---|
| Isaza Ospina | Ecuador, Colombia |
Laura, Marina, Alexander, Luz Aleida, and Sebastián