Last name Destain (Destain 
) , globally, is a rare family name. The surname Destain is habitual in Belgium, where it is a rare surname, France, and Argentina, where it is a very rare surname. More prevalently, Destain is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Destain | Belgium, Democratic Republic of the Congo, Argentina, United States, France |
| françois destain painter (1685-1760), BE (b. 1685) |
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| robert destain French actor and singer, FR (b. 1919) |
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| joseph gabriel destain French architect, FR |
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| jacqueline destain |
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