Last name De Leon (De Leon 
) , worldwide, is a widespread cognomen. The surname De Leon is characteristic of Latin America and the Caribbean, particularly Guatemala, where it is a common surname, the Dominican Republic, and Panama (explore the name in all countries). Measured by absolute frequency, the name is most common in Philippines, Mexico, and Guatemala.
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| De Leon | Guatemala, Mexico, Philippines, United States, Dominican Republic |
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david camden de leon surgeon (b. 1816) |
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| edwin de leon American diplomat, US (b. 1818) |
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sylvia de leon chalreo Brazilian journalist and writer, BR (b. 1905) |
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joey de leon Filipino actor and comedian, PH (b. 1946) |
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rudy de leon United States politician, US (b. 1952) |
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| francisco mendoza de leon Philippino cleric and Bishop of Antipolo, PH (b. 1947) |
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| william de leon William has over 25 years experience in investment management and portfolio risk management having held senior executive positions at the world's leading investment management firms., US (b. 1967) |
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| mario de leon Italian American musician, US (b. 1974) |
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| viridiana alicia lourdes de leon Ph.D. Duke University 2000 |
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| marino de leon researcher |
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| daniel de leon American soccer player, US |
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