Family name Amvouli-Issa (Amvouli-Issa 
) , globally, is a rare cognomen. The family name Amvouli-Issa is characteristic of Sub-Saharan Africa, particularly the Democratic Republic of the Congo, where it is a rare surname. Parts of the name also exists independently as a last name Amvouli, and a last name Issa.
| VARIANT | COUNTRY |
|---|---|
| Amvouli-Issa | Democratic Republic of the Congo |