Cognomen 手島 (手島) , globally, is an extremely rare last name.
| 手島守之輔 JP (b. 1914) |
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| 手島猛 Japanese fencer, JP (b. 1941) |
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| 手島浩之 Japanese architect, JP (b. 1967) |
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| 手島和希 Japanese association football player, JP (b. 1979) |
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| 手島雄介 Japanese motorcycle racer, JP (b. 1983) |
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| 手島千尋 Japanese announcer, JP (b. 1987) |
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