Family name אפרים-יצחק (אפרים-יצחק 
) , worldwide, is an extremely rare cognomen. Much more frequently, אפרים-יצחק is the forename as well as the last name. Parts of the name also exists independently as a first name אפרים, and a first name יצחק.
| VARIANT | COUNTRY |
|---|---|
| אפרים-יצחק | Israel |