Family name Панайотис (Panagiotis 
, Παναγιώτης , Panayotis 
, among others...) , all over the world, is a widespread last name. The surname Панайотис is characteristic of Greece, where it is a prevalent surname, North Macedonia, where it is quite a rare surname, and Cyprus. Not in comparison with a country's population, it is the most numerous in Greece, Bulgaria, and North Macedonia. Also, Панайотис is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Panagiotis | Germany, Cyprus, United Kingdom, United States, Greece |
| Παναγιώτης | Greece |
| Panayotis | Germany, United Kingdom, South Africa, United States, Greece |
| Panajotis | Germany, South Africa, North Macedonia, United States, Greece |
| Panagiotes | Germany, South Africa, United States, Greece, Brazil |
| Панайотис | Russia, Ukraine, Bulgaria |