Last name Исен (Isen 
, Исен 
, Ysen 
) , globally, is quite a rare family name. The family name Исен is habitual in North Macedonia, where it is quite a common surname, Denmark, where it is quite a rare surname, and Hong Kong, where it is a rare surname. Measured by absolute frequency, it most frequently occurs in North Macedonia, the United States, and Germany. Likewise, Исен is the forename as well as the last name.