Cognomen Σπυρίδων (Spyridon 
, Spyros , Spiridon 
, among others...) , across the world, is a widespread surname. The last name Σπυρίδων is habitual in Greece, where it is a prevalent surname, Romania, where it is quite a common surname, and Georgia, where it is quite a rare surname. In absolute terms, this name is the most popular in Greece, Romania, and Bulgaria. Also, Σπυρίδων is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Spyridon, Spyros | Cyprus, Romania, Italy, United States, Greece |
| Spiridon | Romania, Italy, Bulgaria, United States, Greece |
| Спиридон | Kazakhstan, Armenia, Russia, Bulgaria, Ukraine |
| Spiridione | United Kingdom, Italy, United States, Argentina, France |
| Σπυρίδων | Greece |
| Spiridion | Romania, United Kingdom, United States, Greece, France |
| Spirydon | Poland, United Kingdom, United States |
| Спірідон | Ukraine |
| γεώργιος σπυρίδων GR (b. 1800) |
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| άγγελος σπυρίδων Greek association football player, GR (b. 1946) |
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| σπύρος σπυρίδων Greek politician, GR (b. 1954) |
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