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Globally, Мануеле (Manuele , Мануеле ) is quite a common primarily male, but very seldom girly first name. The first name Мануеле is characteristic of British Virgin Islands, where it is quite a common male name, Italy, where it is quite a rare boy's name, and Switzerland, where it is a rare masculine name. Not in comparison with a country's population, this name is the most popular in Italy, Brazil, and France. Very seldom, Мануеле is the last name as well as the forename.
Мануеле is also a name for the fictitious and mythical characters: Manuele Biffi , the operatic character in the opera Giuditta, Si j'étais roi.