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Throughout the world, Sixtus (Sixtus , Сикст ) is quite a rare masculine forename. The first name Sixtus is habitual in Tanzania, where it is quite a rare masculine name, Qatar, and Cameroon, where it is a rare boy's name. Measured by absolute frequency, it is commonest in Sub-Saharan Africa, particularly Nigeria, Tanzania, and South Africa. Likewise, Sixtus is the last name as well as the forename.
Sixtus is also a name for the fictitious and mythical characters: Sixtus Beckmesser , the operatic character in the opera Die Meistersinger von Nürnberg by Richard Wagner.