Worldwide, Santa Luisa (Santa Luisa 
) is a rare girly given name. The forename Santa Luisa is habitual in Latin America and the Caribbean, particularly Peru, where it is a rare female name, Argentina, where it is a very rare girly name, and Mexico. Much less frequently, Santa Luisa is the last name as well as the forename.
| VARIANT | COUNTRY |
|---|---|
| Santa Luisa | Mexico, Argentina, Peru, Italy, Ecuador |