In all the world, O'Brien (O'Brien 
, オブライエン 
, О'Брайен 
) is a rare predominantly male, but very infrequently feminine first name. The first name O'Brien is habitual in Jamaica, where it is a rare male name, Kenya, and South Africa, where it is a very rare boy's name. Predominantly, O'Brien is the last name as well as the forename.
O'Brien is also a name for the fictitious and mythical characters: .
| murtough o'brien Irish bishop (b. 1540) |
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fitz james o'brien Union Army officer, IE (b. 1828) |
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| donat o'brien Irish naval officer (b. 1785) |
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miles m. o'brien American banker, US (b. 1852) |
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darby o'brien American baseball player, US (b. 1863) |
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| loughlin o'brien New Zealand politician, NZ (b. 1820) |
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buck o'brien Major League Baseball pitcher, US (b. 1882) |
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willis o'brien American animator, US (b. 1886) |
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| b. f. o'brien American politician, US (b. 1847) |
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norton c. o'brien politician in Massachusetts, US, US (b. 1907) |
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davey o'brien American football player (1917-1977), US (b. 1917) |
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| lewis o'brien Canadian politician, CA (b. 1868) |
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lewis o'brien Australian Aboriginal Kaurna elder, AU (b. 1930) |
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parry o'brien Athletics competitor, shot putter (1932-2007), US (b. 1932) |
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| harvey o'brien Head college football coach for The Citadel Bulldogs (1883-1955), US (b. 1883) |
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