Across the world, Melissa Karen (Melissa Karen 
) is a rare feminine first name. The first name Melissa Karen is habitual in Peru, where it is a rare feminine name, Chile, and Philippines, where it is an extremely rare female name. Much less frequently, Melissa Karen is the last name as well as the forename.
| VARIANT | COUNTRY |
|---|---|
| Melissa Karen | Australia, Peru, Philippines, Chile, Uruguay |