Throughout the world, Karen Luisa (Karen Luisa 
) is a rare feminine forename. The given name Karen Luisa is habitual in Latin America and the Caribbean, particularly Chile, where it is a rare feminine name, and Peru, where it is a very rare feminine name. Much less frequently, Karen Luisa is the last name as well as the forename.
| VARIANT | COUNTRY |
|---|---|
| Karen Luisa | Philippines, Spain, Peru, Ecuador, Chile |