All around the world, محمدخان (محمدخان 
) is a rare boy's given name. The forename محمدخان is characteristic of Afghanistan, where it is quite a rare male name, Saudi Arabia, where it is a rare boy's name, and Iran, where it is a very rare masculine name. Likewise, محمدخان is the last name as well as the forename.
| VARIANT | COUNTRY |
|---|---|
| محمدخان | Turkey, Saudi Arabia, Afghanistan, Iran |
| محمدخان استاجلو 16th-century Safavid official, AM (b. 1501) |
|
|
| محمدخان دشتی Iranian poet, IR (b. 1852) |
|