Throughout the world, محمدحسین (محمدحسین 
, Mohammad-Hossein 
) is quite a rare boy's first name. The forename محمدحسین is habitual in Afghanistan, where it is quite a rare male name, Iran, where it is a rare boy's name, and Saudi Arabia, where it is a very rare boy's name. Very seldom, محمدحسین is the last name as well as the forename.
| VARIANT | COUNTRY |
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| محمدحسین | Turkey, Afghanistan, Iran, Saudi Arabia |
| Mohammad-Hossein | Spain, France, Iran, Germany |
| محمدحسین صنیع‌خاتم Iranian Khatamkar, IR (b. 1262) |
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| محمدحسین بن خلف تبریزی Iranian writer, IR (b. 1600) |
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| محمدحسین تبریزی Iranian calligrapher, IR (b. 1600) |
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محمدحسین فشارکی IR (b. 1849) |
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محمدحسین نائینی Iranian Islamic scholar (1869-1936), IR (b. 1869) |
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محمدحسین خان مکری Iranian politician, IR (b. 1879) |
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محمدحسین آیرم Iranian general, IR (b. 1882) |
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محمدحسین رکن‌زاده آدمیّت Iranian journalist, writer and poet, IR (b. 1900) |
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محمدحسین مشایخ فریدنی Iranian politician, IR (b. 1914) |
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محمدحسین موسوی Iranian politician, IR (b. 1919) |
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محمدحسین صادقی نیلی Political leader, AF (b. 1940) |
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| محمدحسین فیروز Qajar prince, IR (b. 1894) |
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محمدحسین مقیمی Iranian politician, IR (b. 1950) |
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محمدحسین صفار هرندی Iranian politician, IR (b. 1953) |
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محمدحسین عادلی Academic, diplomat, economist, politician, IR (b. 1953) |
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عظیمی, احمدی, حسینی, حبیبی, حمیدی, رحیمی, صادقی, صداقت, امیری, محمدی, یوسفی, سمنگانی, سهرابی, حیدرزاده, میرزایی, سلطانی, شیرزاد, کریمی, چراغی, کاظمی, مجیدی, حکیمی, رضای, صفری, عسکری, حسنی, رضایی, خاشع, نظری, نوری, کرمی, اصغری, عالمی, حیدری, جعفری, صفدری, غلامی, مرادی, محمودی, and محمد حسین