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Globally, Деспина (Despoina , Despina , Деспина ) is a widespread female first name. The first name Деспина is characteristic of Greece, where it is a prevalent girly name, Cyprus, where it is quite a common female name, and North Macedonia, where it is quite a rare feminine name. Measured by absolute frequency, the name is most common in Greece, the United States, and Bulgaria. Likewise, Деспина is the last name as well as the forename.
Деспина is also a name for the fictitious and mythical characters: Despoina , the Greek goddess of Arcadian mystery cults; Despina , the operatic character in the opera Arrighetto by Carlo Coccia; Corrado's daughter; Despina , the operatic character in the opera Così fan tutte by Wolfgang Amadeus Mozart; a maid; Despoina , the theatrical character in the play "The Festival" and Despina , the operatic character in the opera L’amore innocente, L'amore innocente, among other works.