Last name Wykoff (Wykoff 
) , in the world, is quite a rare surname. The last name Wykoff is characteristic of the United States, where it is a rare surname, New Zealand, where it is a very rare surname, and Australia. In absolute terms, it is the most numerous in the United States, Canada, and Australia.
| VARIANT | COUNTRY |
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| Wykoff | Philippines, Canada, France, United States, Australia |
| margaret wykoff 1693 - 31 Dec 1754 (b. 1693) |
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frank wykoff American athlete, US (b. 1909) |
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| m. william wykoff (b. 1934) |
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| frank c. wykoff (b. 1942) |
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| norman lowell wykoff Ph.D. Indiana University 1974 |
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| frank champion wykoff Ph.D. University of California, Berkeley 1968 |
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| charles c wykoff researcher (ORCID 0000-0001-7756-5091) |
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| dennis d wykoff researcher (ORCID 0000-0003-0178-548X) |
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