Surname Twaddell (Twaddell 
) , globally, is a rare last name. The family name Twaddell is habitual in Australia, where it is a rare surname, Ireland, and New Zealand. In absolute terms, it most frequently occurs in the United States, Australia, and the United Kingdom.
| VARIANT | COUNTRY |
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| Twaddell | United Kingdom, Australia, Ireland, United States, New Zealand |
| william twaddell British politician (b. 1884) |
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| william freeman twaddell American academic, US (b. 1906) |
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| william h. twaddell American diplomat (b. 1941) |
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| william s twaddell researcher |
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