Cognomen Sisto (Sisto 
, Sextus 
, Сикст 
) , in the entire world, is quite a common surname. The surname Sisto is habitual in Uruguay, where it is quite a rare surname, Italy, and Argentina. In absolute terms, it most frequently occurs in Italy, the United States, and Argentina. Likewise, Sisto is the forename as well as the last name.
| genaro sisto AR (b. 1870) |
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| ernie sisto American photographer, US (b. 1904) |
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francesco paolo sisto Italian politician, IT (b. 1955) |
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oscar sisto Argentinian composer, actor and theatre director, AR (b. 1957) |
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rafael sisto Spanish politician, ES (b. 1963) |
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| mikko sisto Finnish lieutenant general (1915-2005), FI (b. 1915) |
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| giovanni sisto Italian politician, IT (b. 1916) |
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jeremy sisto American actor (born 1974), US (b. 1974) |
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| elena sisto American painter, US (b. 1952) |
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| rocco sisto American actor, US (b. 1953) |
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| ezio sisto Italian journalist, IT (b. 1956) |
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| celso sisto Brazilian writer, BR (b. 1961) |
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| pascual sisto Filmmaker and visual artist, ES (b. 1975) |
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| michele sisto Italian germanist (1976-), IT (b. 1976) |
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| gianfrancesco sisto (b. 1967) |
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