Last name Puopolo (Puopolo 
) , in the entire world, is quite a rare family name. The cognomen Puopolo is characteristic of Liechtenstein, where it is quite a common surname, Italy, where it is quite a rare surname, and Switzerland, where it is a rare surname. Measured by absolute frequency, this name is the most popular in Italy, the United States, and Canada. Much less frequently, Puopolo is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Puopolo | Italy, Argentina, United States, Australia, Canada |
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paul puopolo Australian rules footballer, AU (b. 1987) |
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candace puopolo US (b. 1980) |
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| gus puopolo Australian hammer thrower, AU (b. 1948) |
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| ivan puopolo Finnish journalist, FI (b. 1978) |
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| andrew puopolo player of American football, US |
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| rosanna puopolo researcher (ORCID 0000-0002-7640-5384) |
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| karen m puopolo researcher |
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| michelino puopolo researcher |
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| maria puopolo researcher |
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| gerardo puopolo researcher |
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| l.a. puopolo |
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| louis puopolo |
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| carmelina puopolo Canadian association football player, CA (b. 1992) |
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