Last name Orobio (Orobio 
) , in all the world, is quite a rare cognomen. The family name Orobio is characteristic of Latin America and the Caribbean, particularly Colombia, where it is quite a rare surname, Panama, and Mexico, where it is a rare surname. In absolute terms, it is the most numerous in Colombia, Mexico, and Philippines. Very seldom, Orobio is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Orobio | Mexico, Panama, Philippines, Colombia, United States |
| prudencio de orobio y basterra Spanish colonial governor, ES (b. 1800) |
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| jessica orobio researcher (ORCID 0000-0002-7668-2680) |
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| javier orobio Colombian association football player (1996-), CO (b. 1996) |
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| anthony orobio EC (b. 1999) |
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Mr, Lida, Lucy, Luis, Jair, Jose, John, Joan, Joel, Jean, Juan, Jhon, Tata, Tawi, Tomi, Nico, Elsa, Eddy, Edna, Ever, Hans, Hugo, Lina, Gina, Dora, Daly, Ms, Ana, Kim, Ray, Leo, Liz, Luz, Jay, Joe, Jim, Vero, Eva, Yei, Mari, Mary, Sara, Alex, Alma, Aida, Raul, Rosa, Dana, Vã, and Flor