Cognomen Isernia (Isernia 
) , in the entire world, is quite a rare surname. The cognomen Isernia is habitual in Italy, where it is quite a rare surname, Argentina, where it is a rare surname, and Canada. In absolute terms, this name is the most popular in Italy, the United States, and Argentina. Very seldom, Isernia is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Isernia | Canada, Argentina, France, Italy, United States |
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andrea da isernia Italian jurist, IT (b. 1230) |
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| heinrich von isernia (b. 1200) |
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enrico isernia journalist and historian (1831-1907), IT (b. 1831) |
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| gino collenea isernia Italian writer, IT (b. 1937) |
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| pierangelo isernia Italian political scientist (1958-), IT (b. 1958) |
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| tommaso isernia researcher |
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| sara isernia researcher |
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| giacomo isernia researcher |
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| carla isernia researcher ORCID ID = 0000-0002-1504-2479 |
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| benedetto da isernia IT |
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| carla isernia |
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| benedictus de isernia |
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