Surname Panayotou (Panayotou 
) , around the globe, is a rare family name. The cognomen Panayotou is characteristic of Cyprus, where it is quite a rare surname, Greece, where it is a rare surname, and Belgium. Measured by absolute frequency, it most frequently occurs in Australia, France, and Greece. Very seldom, Panayotou is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Panayotou | United Kingdom, United States, Greece, France, Australia |
| maria panayotou Righteous Among the Nations, GR (b. 1893) |
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| antonia panayotou GR (b. 1914) |
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| nikolaos panayotou GR (b. 1914) |
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| angelos panayotou GR (b. 1942) |
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Mr, Carol, Kelly, Panos, Peter, Rhian, Donna, Laura, Louis, Jason, Julia, Nikos, Eleni, Vitor, Frank, Irene, Marion, Silene, Sophia, Alycia, Arthur, Athina, Chris, Ambre, Anton, Sonny, Ms, Jay, Eri, Ino, Zoe, Mary, Alex, Anna, Bill, Kate, Brenna, Paul, Demi, Jack, John, Joel, Jean, Theo, Tony, Nick, Evan, Maria, Popy, and Kostas