Surname Holzapfel (Holzapfel 
, Holsapple 
) , globally, is a common family name. The family name Holzapfel is characteristic of Western Europe, particularly Germany, where it is quite a rare surname, Austria, and Switzerland. Not in comparison with a country's population, it most frequently occurs in Germany, the United States, and Austria.
| VARIANT | COUNTRY |
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| Holzapfel | Switzerland, United States, Germany, Brazil, Austria |
| Holsapple | Switzerland, United States, United Kingdom, New Zealand, Canada |
| johann holzapfel DE (b. 1678) |
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| samuel christlieb holzapfel (b. 1735) |
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| johann gottlob holzapfel DE (b. 1737) |
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| johann tobias gottlieb holzapfel (b. 1773) |
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| johann sebastian gottfried holzapfel DE (b. 1788) |
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| georg christian wilhelm holzapfel DE (b. 1790) |
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| ignacij holzapfel SI (b. 1799) |
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| joseph holzapfel (1815-1854), AT (b. 1815) |
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| rudolph holzapfel (b. 1811) |
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rudolf maria holzapfel Austrian philosopher, AT (b. 1874) |
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| theodor holzapfel AT (b. 1828) |
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| nikolaus holzapfel German politician and farmer (1847-1920), DE (b. 1847) |
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friedrich holzapfel German politician (1900-1969), DE (b. 1900) |
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| ludwig holzapfel German historian, DE (b. 1852) |
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| eduard holzapfel German paleontologist (1853-1913), DE (b. 1853) |
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