Family name Holtgrewe (Holtgrewe 
) , in the world, is a rare cognomen. The surname Holtgrewe is habitual in Germany, where it is a rare surname, the United States, where it is a very rare surname, and Canada, where it is an extremely rare surname.
| VARIANT | COUNTRY |
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| Holtgrewe | Canada, Germany, United States |
| manuel holtgrewe researcher (ORCID 0000-0002-3051-1763) |
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| kris holtgrewe researcher (ORCID 0000-0002-6166-1254) |
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| jeff holtgrewe college basketball player (1975–1978) Oral Roberts |
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| detlev holtgrewe |
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Mr, Kirk, Paul, Rosa, Rick, Ruth, Ryan, Dare, Dave, Gary, Greg, Gwen, Lois, Luke, Jane, Jake, Josh, John, Joan, Jody, Jean, Judy, Kent, Cody, Adam, Aron, Ms, Bj, Ty, Max, Sam, Ann, Art, Ken, Kim, Dan, Tara, Jan, Jim, Tom, Tim, Mary, Mara, Sara, Seth, Sven, Alan, Anna, Joe, and Theo