Cognomen Fragene (Fragene 
) , worldwide, is a very rare surname. The cognomen Fragene is habitual in Nigeria, where it is a very rare surname, and the United States, where it is an extremely rare surname. More prevalently, Fragene is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Fragene | Nigeria, United States, Democratic Republic of the Congo |