Surname Esmedio (Esmedio 
) , in all the world, is a rare family name. The cognomen Esmedio is habitual in Philippines, where it is a rare surname, and Brazil, where it is an extremely rare surname. Much less frequently, Esmedio is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Esmedio | Philippines, Brazil |
Rey, Jesusa, Vaniza, Oliver, Ofelia, Marites, Ma. Lea, Mildred, Mirasol, Annalyn, Armando, Casilda, Romegio, Renalyn, Richard, Rizaldy, Edgardo, Vitalia, William, Mary Ann, Monsueto, Manuelito, Joseph, Roland, Rafael, Porcia, Mark, Mhel, Gina, Jose, Nora, Edna, Maria, Melba, Sally, Ariel, Aparecida, Perla, Rodel, Rizza, Diana, Janno, Tomas, Manuel, Manolo, Matias, Chuche, Krizha, Ramil, and Christina