Last name Destefanis (Destefanis 
) , worldwide, is quite a rare cognomen. The surname Destefanis is characteristic of Italy, where it is quite a rare surname, Argentina, and France, where it is a rare surname. Measured by absolute frequency, it most frequently occurs in Italy, Argentina, and the United States. Very seldom, Destefanis is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Destefanis | Hong Kong, France, Argentina, Italy, United States |
Destéfanis, and Дестефаніс
| giovanni giuseppe destefanis (b. 1700) |
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| sergio pietro destefanis Italian economist, IT (b. 1958) |
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| carla destefanis Peerage person ID=720288 (b. 1966) |
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| modesto destefanis Italian politician |
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| francesca destefanis researcher |
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| paolo destefanis researcher |
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| nancy destefanis American naturalist and environmental educator |
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| eliana destefanis researcher |
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| giovanni destefanis Italian racing cyclist, IT |
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| marco giovanni maria destefanis researcher |
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| eleonora destefanis IT |
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