Cognomen Defelice (De Felice 
, Defelice 
) , across the world, is a common last name. The surname Defelice is habitual in Italy, where it is quite a common surname, Argentina, where it is quite a rare surname, and Paraguay. Not in comparison with a country's population, the name is most common in Italy, the United States, and Argentina.
| VARIANT | COUNTRY |
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| De Felice | Italy, France, Paraguay, United States, Argentina |
| Defelice | Italy, France, Canada, United States, Argentina |
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joseph defelice American politician, US |
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jonathan defelice American college president |
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| norm defelice Canadian ice hockey player, CA (b. 1933) |
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| stephen l. defelice American physician and writer, US (b. 1936) |
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| nick defelice American football tackle, US (b. 1940) |
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| cynthia defelice American children's writer, US (b. 1951) |
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| jim defelice US author (1956-), US (b. 1956) |
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| garth defelice American football official |
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| mialy m defelice researcher (ORCID 0000-0002-7197-6292) |
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| ron defelice artist |
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| nicholas b defelice researcher |
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| matthew defelice researcher |
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| brian c defelice |
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| fabio defelice |
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